VPOC stands for Volume Point of Control. It is the single price level — one tick — where the greatest cumulative volume has traded during the current session. Not the highest price, not the average price, not the open or the close. The price where the most contracts changed hands.
To find it, you build a horizontal histogram with price on the vertical axis and traded volume on the horizontal axis. The longest bar — the price level with the largest cumulative volume — is the VPOC. Every other level on the profile is measured relative to it.
The VPOC moves throughout the session. As trade prints accumulate, a new price level can overtake the previous VPOC in cumulative volume, and the VPOC migrates to that new level. This migration is itself a signal — but that's a topic for another page.